Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373838 | 0.82 | KDM4E (0.62) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL3578797 | 0.82 | KDM4E (0.62) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8307320 | 0.80 | KDM4E (0.61) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL4166587 | 0.79 | KDM4E (0.46) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL15209096 | 0.78 | KDM4E (0.59) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28348295 | 0.78 | KDM4E (0.44) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL1095 | 0.78 | PIM3 (0.49) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10919018 | 0.76 | PIM3 (0.47) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL15230652 | 0.76 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL28285912 | 0.76 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536586-B | Pyrazole amide compound as well as preparation method and application thereof | 华东理工大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-115536586-A | Pyrazole amide compounds and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |
| EP-0590720-A1 | Pyrazolecarboxamides exhibiting insecticidal and acaricidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-04-06 | — | — | EP | disclosed |