Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LDLR | P01130 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9411311 | 0.97 | KMT2A (0.46) | KMT2APKMHDAC3HDAC4HDAC1 | |
| SCHEMBL9411461 | 0.92 | KMT2A (0.47) | KMT2APKMACHEKDM4EMAPT | |
| Acetic Acid SCHEMBL9411399 | 0.91 | KMT2A (0.47) | KMT2APKMACHEKDM4EMAPT | |
| SCHEMBL9411354 | 0.88 | KMT2A (0.52) | KMT2APKMHDAC3HDAC4HDAC1 | |
| SCHEMBL9411300 | 0.86 | ACHE (0.45) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9411541 | 0.84 | RAB9A (0.45) | KMT2APKMACHEKDM4EMAPT | |
| Acetic Acid SCHEMBL9411605 | 0.83 | RAB9A (0.44) | KMT2APKMACHEKDM4EMAPT | |
| SCHEMBL9411597 | 0.80 | KMT2A (0.51) | KMT2APKMACHEKDM4EMAPT | |
| SCHEMBL9411390 | 0.79 | RAB9A (0.42) | KMT2APKMACHEKDM4EMAPT | |
| SCHEMBL9411307 | 0.79 | ACHE (0.45) | KMT2AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |