SCHEMBL9411337

SCHEMBL9411337

Cc1ccc2c(OCCC3CCN(Cc4ccccc4)CC3)noc2c1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 18/20 0.62
DRD2 P14416 1/20 0.51
DRD4 P21917 1/20 0.51
BCHE P06276 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9411261 0.92 ACHE (0.70) ACHEDRD2DRD4BCHE
SCHEMBL9411254 0.90 ACHE (0.52) ACHEDRD2
SCHEMBL9411640 0.90 ACHE (0.50) ACHEDRD2DRD4
SCHEMBL9411412 0.88 ACHE (0.61) ACHEDRD2
SCHEMBL9411273 0.87 ACHE (0.79) ACHEDRD2DRD4BCHE
SCHEMBL9411607 0.86 SLC6A4 (0.48) ACHEDRD2DRD4
SCHEMBL9411458 0.85 ACHE (0.52) ACHE
Fumaric Acid SCHEMBL9411651 0.85 ACHE (0.61) ACHEDRD2DRD4BCHE
Fumaric Acid SCHEMBL9411650 0.85 ACHE (0.61) ACHEDRD2DRD4BCHE
Fumaric Acid SCHEMBL9411238 0.84 ACHE (0.50) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602242-A1 BENZISOXAZOLE COMPOUND AND USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-06-22 EP disclosed