Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411337 | 0.90 | ACHE (0.62) | ACHEDRD2DRD4 | |
| SCHEMBL9411462 | 0.89 | SLC6A2 (0.57) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| Fumaric Acid SCHEMBL9411247 | 0.86 | ACHE (0.52) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| Fumaric Acid SCHEMBL9411250 | 0.86 | ACHE (0.52) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL9411607 | 0.85 | SLC6A4 (0.48) | ACHESLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL9411323 | 0.85 | SLC6A2 (0.54) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL9411468 | 0.84 | MCHR1 (0.52) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL9411254 | 0.82 | ACHE (0.52) | ACHEDRD2 | |
| SCHEMBL9411261 | 0.82 | ACHE (0.70) | ACHEDRD2DRD4 | |
| SCHEMBL9411555 | 0.79 | ACHE (0.41) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |