Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.62 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411516 | 0.94 | ACHE (0.62) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411346 | 0.89 | ACHE (0.77) | ACHE | |
| SCHEMBL9411538 | 0.89 | ACHE (0.67) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411429 | 0.87 | ACHE (0.63) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411424 | 0.85 | ACHE (0.64) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411323 | 0.85 | SLC6A2 (0.54) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411470 | 0.85 | ACHE (0.59) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411480 | 0.83 | ACHE (0.77) | ACHE | |
| SCHEMBL9411441 | 0.83 | ACHE (0.67) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411418 | 0.83 | ACHE (0.63) | ACHEDRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |