Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.67 |
| ▸ | DRD2 | P14416 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | HTR7 | P34969 | 4/20 | 0.59 |
| ▸ | HTR6 | P50406 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411429 | 0.95 | ACHE (0.63) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411424 | 0.94 | ACHE (0.64) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411346 | 0.94 | ACHE (0.77) | ACHE | |
| SCHEMBL9411441 | 0.94 | ACHE (0.67) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411579 | 0.91 | DRD2 (0.60) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411359 | 0.89 | ACHE (0.62) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411561 | 0.88 | ACHE (0.64) | ACHE | |
| SCHEMBL9411655 | 0.88 | ACHE (0.64) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL9411480 | 0.87 | ACHE (0.77) | ACHE | |
| SCHEMBL9411433 | 0.85 | ACHE (0.65) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |