Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 13/20 | 0.46 |
| ▸ | ACHE | P22303 | 11/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | QDPR | P09417 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411589 | 0.93 | MAPT (0.44) | HTR4ACHEMAPTTDP1DRD2 | |
| SCHEMBL9411299 | 0.88 | MAPT (0.48) | MAPTTDP1QDPRALDH1A1L3MBTL1 | |
| SCHEMBL9411362 | 0.87 | MAPT (0.42) | HTR4ACHEMAPTTDP1DRD2 | |
| Acetic Acid SCHEMBL9411324 | 0.85 | MAPT (0.43) | HTR4ACHEMAPTTDP1DRD2 | |
| SCHEMBL9411321 | 0.83 | HTR4 (0.42) | HTR4ACHEDRD2DRD4ALDH1A1 | |
| SCHEMBL9411376 | 0.78 | HPGD (0.48) | HTR4ACHEMAPTDRD2DRD4 | |
| SCHEMBL9411316 | 0.77 | ALDH1A1 (0.41) | HTR4ACHEDRD2DRD4QDPR | |
| SCHEMBL4857563 | 0.75 | HTR4 (0.49) | HTR4ACHEALDH1A1L3MBTL1 | |
| SCHEMBL9411365 | 0.73 | MAPT (0.43) | MAPTTDP1QDPRALDH1A1L3MBTL1 | |
| SCHEMBL9411506 | 0.72 | HTR4 (0.44) | HTR4ACHEDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |