Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411387 | 0.86 | ACHE (0.66) | ACHEBCHE | |
| SCHEMBL9411500 | 0.86 | ACHE (0.68) | ACHEBCHE | |
| SCHEMBL4488641 | 0.86 | ACHE (0.79) | ACHEBCHE | |
| SCHEMBL9411486 | 0.83 | ACHE (0.63) | ACHEBCHE | |
| SCHEMBL9411558 | 0.83 | ACHE (0.59) | ACHEBCHE | |
| SCHEMBL9411567 | 0.83 | ACHE (0.58) | ACHEBCHE | |
| SCHEMBL9411583 | 0.82 | ACHE (0.61) | ACHEMEN1KMT2ABCHE | |
| SCHEMBL9411269 | 0.82 | ACHE (0.57) | ACHEBCHE | |
| SCHEMBL9411353 | 0.82 | ACHE (0.57) | ACHEBCHE | |
| SCHEMBL9411341 | 0.82 | ACHE (0.66) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |