Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411643 | 0.90 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL9411387 | 0.86 | ACHE (0.66) | ACHEBCHE | |
| SCHEMBL9411567 | 0.85 | ACHE (0.58) | ACHEBCHEHTR1AHTR1DHTR1B | |
| SCHEMBL9411353 | 0.85 | ACHE (0.57) | ACHEBCHE | |
| SCHEMBL9411500 | 0.84 | ACHE (0.68) | ACHEBCHE | |
| SCHEMBL9411558 | 0.84 | ACHE (0.59) | ACHEBCHE | |
| SCHEMBL9411357 | 0.84 | ACHE (0.54) | ACHEBCHEHTR1AHTR1DHTR1B | |
| SCHEMBL4488641 | 0.84 | ACHE (0.79) | ACHEBCHE | |
| SCHEMBL9411375 | 0.83 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL9411269 | 0.83 | ACHE (0.57) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |