Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 8/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411517 | 0.94 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3CCR3MCHR1 | |
| SCHEMBL9411582 | 0.90 | MCHR1 (0.47) | SLC6A4SLC6A3MCHR1ACHEDRD2 | |
| SCHEMBL9411374 | 0.87 | ACHE (0.43) | MCHR1ACHEHTR2A | |
| SCHEMBL9411393 | 0.85 | SLC6A4 (0.50) | SLC6A4SLC6A3MCHR1ACHEDRD2 | |
| SCHEMBL9411540 | 0.84 | MCHR1 (0.40) | MCHR1ACHEDRD2HTR2AHTR7 | |
| SCHEMBL9411302 | 0.84 | ACHE (0.50) | MCHR1ACHE | |
| SCHEMBL9411448 | 0.83 | MCHR1 (0.48) | SLC6A4SLC6A3MCHR1ACHE | |
| SCHEMBL9411661 | 0.83 | ACHE (0.47) | SLC6A2SLC6A4SLC6A3MCHR1ACHE | |
| SCHEMBL9411512 | 0.82 | KDM4E (0.42) | ACHEDRD2HTR2A | |
| SCHEMBL9411368 | 0.81 | ACHE (0.47) | MCHR1ACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |