Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411368 | 0.95 | ACHE (0.47) | MCHR1KCNH2ACHE | |
| SCHEMBL9411302 | 0.94 | ACHE (0.50) | MCHR1KCNH2ACHE | |
| SCHEMBL9411582 | 0.94 | MCHR1 (0.47) | MCHR1KCNH2SLC6A3SLC6A4ACHE | |
| SCHEMBL9411478 | 0.92 | MCHR1 (0.41) | MCHR1KCNH2ACHE | |
| SCHEMBL9411573 | 0.90 | HTR2A (0.44) | KCNH2SLC6A4 | |
| SCHEMBL9411517 | 0.89 | SLC6A2 (0.52) | MCHR1SLC6A3SLC6A4ACHE | |
| SCHEMBL9411374 | 0.89 | ACHE (0.43) | MCHR1KCNH2ACHE | |
| SCHEMBL9411540 | 0.86 | MCHR1 (0.40) | MCHR1KCNH2ACHE | |
| SCHEMBL9411209 | 0.84 | DRD2 (0.48) | — | |
| SCHEMBL9411621 | 0.84 | OPRM1 (0.44) | KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |