Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 9/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411575 | 0.95 | SLC6A4 (0.57) | SLC6A4SLC6A3ACHEOPRM1OPRK1 | |
| SCHEMBL9411323 | 0.86 | SLC6A2 (0.54) | SLC6A4SLC6A3ACHEDRD2HTR2A | |
| SCHEMBL9411470 | 0.85 | ACHE (0.59) | SLC6A4SLC6A3ACHEDRD2HTR2A | |
| SCHEMBL9411607 | 0.85 | SLC6A4 (0.48) | SLC6A4SLC6A3ACHEOPRM1OPRK1 | |
| SCHEMBL9411496 | 0.84 | HTR1A (0.55) | ACHEDRD2HTR2AHTR1AHRH3 | |
| SCHEMBL9411590 | 0.84 | ACHE (0.46) | ACHEDRD2HTR2AHTR1AHRH3 | |
| SCHEMBL9411635 | 0.83 | ACHE (0.58) | SLC6A4SLC6A3ACHEDRD2HTR2A | |
| SCHEMBL9411659 | 0.81 | HTR1A (0.51) | ACHEDRD2HTR2AHTR1AHRH3 | |
| SCHEMBL9411577 | 0.81 | HTR1A (0.53) | ACHEDRD2HTR2AHTR1AHRH3 | |
| SCHEMBL9411412 | 0.81 | ACHE (0.61) | SLC6A3ACHEDRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |