Known targets — ChEMBL curated mechanism
ADRB1ADRB2ATP4AATP4BAXLCHRM2CHRM3DRD2FLT3HRH1HTR2AHTR2BHTR2CKCNH2KMT2AMAP2K1MAP2K2MEN1MLNRPLK4RENS1PR1SLC6A2SLC6A4atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9411559 | 1.00 | ACHE (0.86) | ACHEBCHE | |
| SCHEMBL9411207 | 0.95 | ACHE (0.86) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6989648 | 0.93 | ACHE (1.00) | ACHEBCHE | |
| Fumaric Acid SCHEMBL7557888 | 0.93 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL252472 | 0.88 | ACHE (1.00) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL9411591 | 0.87 | ACHE (0.98) | ACHEBCHE | |
| Fumaric Acid SCHEMBL6988868 | 0.86 | ACHE (0.85) | ACHEBCHE | |
| Maleic Acid SCHEMBL6988865 | 0.86 | ACHE (0.85) | ACHEBCHE | |
| Fumaric Acid SCHEMBL9411270 | 0.86 | ACHE (0.77) | ACHEBCHE | |
| Fumaric Acid SCHEMBL9411266 | 0.86 | ACHE (0.77) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |