Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716988 | 0.87 | THRB (0.49) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL24278421 | 0.83 | THRB (0.51) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL9246668 | 0.81 | THRB (0.44) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL235466 | 0.81 | THRB (0.46) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL237893 | 0.81 | THRB (0.46) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL15807762 | 0.80 | THRB (0.49) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL238593 | 0.78 | THRB (0.44) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL237184 | 0.78 | THRB (0.44) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL229250 | 0.78 | THRB (0.54) | THRBMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL229372 | 0.78 | THRB (0.54) | THRBMAPTTSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624827-A1 | Method of making micropatterns | CIBA-GEIGY AG (CH) | 1994-11-17 | — | — | EP | disclosed |