Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237882 | 0.89 | THRB (0.46) | THRBTSHRHPGDTHRAALDH1A1 | |
| SCHEMBL237184 | 0.85 | THRB (0.44) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL237893 | 0.85 | THRB (0.46) | THRBTSHRHPGDKMT2ATHRA | |
| SCHEMBL8668333 | 0.83 | THRB (0.47) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL234085 | 0.79 | ALDH1A1 (0.41) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL1716988 | 0.78 | THRB (0.49) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL9411565 | 0.78 | THRB (0.49) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL24278421 | 0.78 | THRB (0.51) | THRBTSHRHPGDTHRAMAPT | |
| SCHEMBL1066824 | 0.77 | THRB (0.49) | THRBTSHRHPGDMEN1KMT2A | |
| SCHEMBL28657837 | 0.77 | THRB (0.52) | THRBTSHRHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |