Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9411472 | 0.93 | ACHE (0.53) | ACHE | |
| Fumaric Acid SCHEMBL9411465 | 0.93 | ACHE (0.53) | ACHE | |
| SCHEMBL9411254 | 0.92 | ACHE (0.52) | ACHEDRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9411564 | 0.91 | ACHE (0.48) | ACHEDRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9411261 | 0.90 | ACHE (0.70) | ACHEDRD2 | |
| SCHEMBL9411222 | 0.88 | ACHE (0.63) | ACHEDRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9411458 | 0.88 | ACHE (0.52) | ACHEKCNH2 | |
| Fumaric Acid SCHEMBL9411235 | 0.86 | ACHE (0.50) | ACHEHTR2A | |
| Fumaric Acid SCHEMBL9411238 | 0.86 | ACHE (0.50) | ACHEHTR2A | |
| SCHEMBL27981554 | 0.84 | ACHE (0.83) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | claimed |
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |