Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.46 |
| ▸ | HTR2A | P28223 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9411665 | 0.91 | ACHE (0.60) | ACHEDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL9411646 | 0.87 | DRD2 (0.56) | ACHEDRD2HTR2AHTR1AHRH3 | |
| Fumaric Acid SCHEMBL9411465 | 0.84 | ACHE (0.53) | ACHE | |
| Fumaric Acid SCHEMBL9411472 | 0.84 | ACHE (0.53) | ACHE | |
| SCHEMBL9411254 | 0.83 | ACHE (0.52) | ACHEDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL9411212 | 0.81 | DRD2 (0.52) | ACHEDRD2HTR2AHTR1AHRH3 | |
| SCHEMBL9411261 | 0.81 | ACHE (0.70) | ACHEDRD2 | |
| SCHEMBL9411358 | 0.80 | ACHE (0.48) | ACHESIGMAR1 | |
| SCHEMBL9411458 | 0.79 | ACHE (0.52) | ACHEHRH3KCNH2 | |
| SCHEMBL9411222 | 0.78 | ACHE (0.63) | ACHEDRD2HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |