Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74206 | 0.71 | DDR1 (0.37) | RIPK1GRM2DDR1 | |
| SCHEMBL8947553 | 0.59 | GRM2 (0.36) | RIPK1GRM2DDR1CACNA1HEGLN1 | |
| SCHEMBL545041 | 0.57 | NOTUM (0.60) | NOTUMGPBAR1 | |
| SCHEMBL2389665 | 0.57 | GPBAR1 (0.48) | NOTUMCTSKKCNH2GPBAR1 | |
| SCHEMBL23065961 | 0.56 | NOTUM (0.54) | NOTUM | |
| SCHEMBL5224905 | 0.56 | SOS1 (0.55) | NOTUM | |
| SCHEMBL25406281 | 0.56 | MLYCD (0.41) | NOTUMGPBAR1 | |
| SCHEMBL23065962 | 0.56 | NOTUM (0.50) | NOTUM | |
| SCHEMBL28749071 | 0.55 | SOS1 (0.61) | NOTUM | |
| SCHEMBL30033650 | 0.55 | CFTR (0.55) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6227919-A | — | — | None | — | — | JP | disclosed |
| JP-H06227919-A | USE OF CN-SUBSTITUTED BENZIMIDAZOLE | BAYER AG | 1994-08-16 | — | — | JP | disclosed |