SCHEMBL74206

SCHEMBL74206

CN(C)S(=O)(=O)n1c(C#N)nc2c(Br)cc(C(F)(F)F)cc21

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 6/20 0.37
GRM2 Q14416 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
RIPK1 Q13546 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947553 0.83 GRM2 (0.36) DDR1GRM2KDM4EGAARIPK1
SCHEMBL11013912 0.79 S1PR1 (0.42) DDR1KDM4EGAASMN1; SMN2
SCHEMBL10961029 0.76 SMN1; SMN2 (0.39) KDM4EGAASMN1; SMN2
SCHEMBL9198138 0.75 THRA (0.33) KDM4EGAA
SCHEMBL9174176 0.73 CACNA1H (0.33) KDM4EGAASMN1; SMN2
SCHEMBL9589303 0.71 LMNA (0.38) SMN1; SMN2
SCHEMBL9411950 0.71 RIPK1 (0.33) DDR1GRM2RIPK1
SCHEMBL10832057 0.68 KDM4E (0.38) KDM4EGAASMN1; SMN2
SCHEMBL9519662 0.67 SMN1; SMN2 (0.33) KDM4EGAASMN1; SMN2
SCHEMBL9074842 0.67 SMN1; SMN2 (0.42) KDM4EGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212881-A1 AN AGROCHEMICAL COMPOSITION UPL LTD (IN) 2025-07-03 US claimed
CN-119012915-A Agrochemical composition UPL有限公司 2024-11-22 CN claimed
WO-2023212494-A2 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-11-02 WO claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
WO-2023180909-A1 AN AGROCHEMICAL COMPOSITION UPL LIMITED (IN) 2023-09-28 WO claimed
WO-2022099169-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-05-12 WO claimed
EP-2507230-B1 INSECTICIDAL COMPOUNDS BASED ON ISOXAZOLINE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-01-17 EP claimed
EP-2331535-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-07-22 EP claimed
EP-2238132-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2012-08-01 EP claimed
US-5468747-A Fungicidal compositions and methods of use employing pyrimidine derivatives ZENECA LIMITED (GB) 1995-11-21 US claimed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 US disclosed
WO-2026088132-A1 COMPOSITIONS COMPRISING SEAWEED EXTRACT UPL MAURITIUS LIMITED (MU) 2026-04-30 WO disclosed
US-20260096568-A1 A POST-HARVEST SOLUTION FOR AGRICULTURAL PRODUCE DECCO WORLDWIDE POST HARVEST HOLDING BV (NL) 2026-04-09 US disclosed
US-20260057963-A1 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATONAL, INC. (US) 2026-02-26 US disclosed
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
EP-0468684-A2 Propenoic acid derivatives, process for their preparation and their use as fungicides ZENECA LIMITED (GB) 1992-01-29 EP disclosed
US-5059605-A Methyl 2-(pyridyloxypyrimidinyleneoxyphenylene)-3-methoxypropenoates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-22 US disclosed
US-5055471-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-08 US disclosed
US-4999381-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-12 US disclosed
EP-0370629-A1 Fungicides ZENECA LIMITED (GB) 1990-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260096568-A1 A POST-HARVEST SOLUTION FOR AGRICULTURAL PRODUCE AGL, ACSL3, NOTUM DDR1 4288/4885GRM2 2781/4885KDM4E 1585/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC DDR1 2574/4885GRM2 1463/4885KDM4E 4269/4885
US-20250212881-A1 AN AGROCHEMICAL COMPOSITION CBR3, BROX, CNPY2 DDR1 4835/4885GRM2 1667/4885KDM4E 1070/4885
US-20260057963-A1 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PAK4, STRAP, MOK DDR1 2623/4885GRM2 386/4885KDM4E 2219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.