SCHEMBL9411994

SCHEMBL9411994

COc1cc(OC)nc(OC(/C=C/c2ccc(Cl)cc2)C(C)(C)C)n1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 11/20 0.46
EDNRA P25101 11/20 0.46
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NFE2L2 Q16236 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.34
AHR P35869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9411998 1.00 EDNRB (0.46) EDNRBEDNRACYP1A2CYP2C9CYP2C19
SCHEMBL9412740 0.73 EDNRB (0.43) EDNRBEDNRAL3MBTL1
SCHEMBL9295985 0.64 EDNRB (0.40) EDNRBEDNRAL3MBTL1
SCHEMBL9367368 0.64 EDNRB (0.38) EDNRBEDNRAL3MBTL1
SCHEMBL9367373 0.64 EDNRB (0.38) EDNRBEDNRAL3MBTL1
SCHEMBL30953547 0.64 AHR (0.43) CYP1A2CYP2C19NPSR1NFE2L2ALDH1A1
SCHEMBL14465008 0.63 AHR (0.48) CYP1A2NFE2L2AHR
SCHEMBL9967711 0.63 AHR (0.48) CYP1A2NFE2L2AHR
SCHEMBL10131184 0.63 AHR (0.48) CYP1A2NFE2L2AHR
SCHEMBL9412032 0.63 MAOA (0.51) CYP1A2CYP2C9CYP2C19ALDH1A1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0611759-A1 Pyrimidinyloxy/triazinyloxy alkanol derivatives and their use as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-08-24 EP disclosed