SCHEMBL30953547

SCHEMBL30953547

COC(C)/C=C/c1ccc(Cl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.43
NFE2L2 Q16236 3/20 0.42
MAOB P27338 2/20 0.42
MAOA P21397 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
THPO P40225 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
GMNN O75496 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9967711 0.83 AHR (0.48) AHRNFE2L2MAOBMAOACYP1A2
SCHEMBL14465008 0.83 AHR (0.48) AHRNFE2L2MAOBMAOACYP1A2
SCHEMBL10131184 0.83 AHR (0.48) AHRNFE2L2MAOBMAOACYP1A2
SCHEMBL30953662 0.82 CYP3A4 (0.57) AHRNFE2L2TP53CYP3A4CYP2D6
SCHEMBL30953550 0.82 RELA (0.55) NFE2L2MAOBMAOATP53CYP3A4
SCHEMBL30953586 0.80 NFE2L2 (0.57) NFE2L2MEN1KMT2ARELAPTGS1
SCHEMBL30953556 0.80 CYP2C19 (0.49) MAOBMAOATP53CYP3A4CYP2D6
SCHEMBL11539633 0.79 TRPA1 (0.52) NFE2L2MAOBTP53CYP3A4MEN1
SCHEMBL12066326 0.79 TRPA1 (0.52) NFE2L2MAOBTP53CYP3A4MEN1
SCHEMBL2077774 0.75 ADRB2 (0.46) AHRNFE2L2MAOBCYP1A2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886677-A Synthesis method of allyl trifluoroethyl ether compound 合肥工业大学 2024-04-16 CN disclosed