SCHEMBL9854147

SCHEMBL9854147

CC(C)(Cn1cncn1)C(O)/C=C/c1ccc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 3/20 0.43
LMNA P02545 2/20 0.43
PKM P14618 2/20 0.43
MAPT P10636 2/20 0.43
HSP90AA1 P07900 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 4/20 0.39
CYP2D6 P10635 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP2C19 P33261 3/20 0.39
KCNH2 Q12809 2/20 0.39
POLB P06746 1/20 0.38
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881186 0.81 ALDH1A1 (0.42) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL9788444 0.76 ALDH1A1 (0.46) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL9788442 0.76 ALDH1A1 (0.46) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL9412002 0.74 MAPT (0.43) ALDH1A1LMNAMAPTSMN1; SMN2KMT2A
SCHEMBL9412005 0.74 MAPT (0.43) ALDH1A1LMNAMAPTSMN1; SMN2KMT2A
SCHEMBL9412000 0.74 MAPT (0.43) ALDH1A1LMNAMAPTSMN1; SMN2KMT2A
SCHEMBL9467875 0.73 MAPT (0.48) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL10625098 0.73 ALDH1A1 (0.48) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL10625096 0.73 ALDH1A1 (0.48) CYP3A4ALDH1A1HPGDLMNAPKM
SCHEMBL9467881 0.73 MAPT (0.48) CYP3A4ALDH1A1HPGDLMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427168-A1 Optical isomer of triazolylpentenols, and their production and use as fungicide, herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-15 EP disclosed
EP-0175278-A2 Optical isomer of triazolylpentenols, and their production and use as fungicide herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-03-26 EP disclosed
EP-0121284-A2 (+)-Triazolylpentenol derivative, its production and use as herbicide and/or plant growth regulant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-10-10 EP disclosed
US-4435203-A 1-(4-CHLORO- OR 2,4-DICHLORO-PHENYL)-2-(1,2,4-TRIAZOL-1-YL)-4,4-DIMETHYLPENT-1-EN-3-OL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-06 US disclosed
EP-0054431-A1 Optical isomer of a triazolylpentenol, and its production and use as fungicide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-23 EP disclosed