SCHEMBL941222

SCHEMBL941222

CN(CC(=O)OC(=O)CCC(=O)OC(=O)CN(C)C(=N)N)C(=N)N

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
CA1 P00915 17/20 0.36
CA2 P00918 17/20 0.36
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3812152 0.94 NOS3 (0.39) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL21404095 0.92 NOS3 (0.38) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL29175400 0.92 NOS3 (0.38) ALDH1A1NOS3NOS1NOS2CA1
Water SCHEMBL21810558 0.92 NOS3 (0.38) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL3817553 0.91 ALDH1A1 (0.54) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL28959584 0.90 NOS3 (0.34) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL1242115 0.90 CA1 (0.34) ALDH1A1NOS3NOS1NOS2CA1
SCHEMBL21404061 0.88 CA1 (0.39) NOS3NOS1NOS2CA1CA2
SCHEMBL584167 0.86 NOS3 (0.35) NOS3NOS1NOS2CA1CA2
SCHEMBL5345186 0.86 CA1 (0.36) NOS3NOS1NOS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3908297-B1 FIBROBLAST REGENERATIVE CELLS SPINALCYTE LLC (US) 2025-10-22 EP claimed
US-20220110979-A1 FIBROBLAST REGENERATIVE CELLS FIGENE, LLC 2022-04-14 US claimed
EP-3908297-A1 FIBROBLAST REGENERATIVE CELLS Figene, LLC (US) 2021-11-17 EP claimed
WO-2020146874-A1 FIBROBLAST REGENERATIVE CELLS FIGENE, LLC (US) 2020-07-16 WO claimed
US-9855296-B2 Methods and compositions for mitochondrial replacement therapy THE MCLEAN HOSPITAL CORPORATION (US) 2018-01-02 US claimed
US-9603872-B2 Methods and compositions for mitochondrial replacement therapy The McLeon Hospital Corporation (US) 2017-03-28 US claimed
US-20170065635-A1 METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY THE MCLEAN HOSPITAL CORPORATION 2017-03-09 US claimed
EP-2641617-A1 Methods and compositions for mitochondrial replacement therapy THE McLEAN HOSPITAL CORPORATION (US) 2013-09-25 EP claimed
US-20110008310-A1 METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY THE MCLEAN HOSPITAL CORPORATION (US) 2011-01-13 US claimed
EP-2150117-A1 METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY The McLean Hospital Corporation (US) 2010-02-10 EP claimed
WO-2008137035-A1 METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY THE MCLEAN HOSPITAL CORPORATION (US) 2008-11-13 WO claimed
US-7226947-B1 Use of creatine as a fat substitute ALZCHEM TROSTBERG GMBH (DE) 2007-06-05 US claimed
CN-1224328-C Use of creatine as fodder additive DSM FINE CHEM AUSTRIA GMBH (AT) 2005-10-26 CN claimed
EP-1176875-B1 USE OF CREATINE AS A FEED SUBSTITUTE DSM FINE CHEM AUSTRIA GMBH (AT) 2005-01-19 EP claimed
CN-1350434-A Use of creatine as fodder additive DSM FINE CHEMICALS AUSTRIA (AT) 2002-05-22 CN claimed
EP-3908297-B1 FIBROBLAST REGENERATIVE CELLS SPINALCYTE LLC (US) 2025-10-22 EP disclosed
US-20240238337-A1 COMPOSITIONS OF FUNCTIONAL MITOCHONDRIA AND USES THEREOF MINOVIA THERAPEUTICS LTD. (IL) 2024-07-18 US disclosed
US-7226947-B1 Use of creatine as a fat substitute ALZCHEM TROSTBERG GMBH (DE) 2007-06-05 US disclosed
CN-1224328-C Use of creatine as fodder additive DSM FINE CHEM AUSTRIA GMBH (AT) 2005-10-26 CN disclosed
CN-1350434-A Use of creatine as fodder additive DSM FINE CHEMICALS AUSTRIA (AT) 2002-05-22 CN disclosed