Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412303 | 0.90 | ALDH1A1 (0.36) | ALDH1A1MAPTRECQL | |
| SCHEMBL9412290 | 0.86 | RECQL (0.34) | ALDH1A1MAPTRECQLTP53TSHR | |
| SCHEMBL9412296 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTRECQL | |
| SCHEMBL8996591 | 0.81 | ALDH1A1 (0.35) | ALDH1A1MAPTTP53TSHRMAPK1 | |
| SCHEMBL9412247 | 0.80 | RECQL (0.36) | ALDH1A1MAPTRECQLTP53TSHR | |
| SCHEMBL9412276 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTRECQLTP53TSHR | |
| SCHEMBL9412224 | 0.77 | FNTA (0.33) | ALDH1A1MAPTTP53TSHRMAPK1 | |
| SCHEMBL9412295 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MAPTRECQLTP53TSHR | |
| SCHEMBL9412298 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTRECQLMAPK1HSD17B10 | |
| SCHEMBL9412299 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578246-A1 | Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1994-01-12 | — | — | EP | disclosed |