SCHEMBL9412299

SCHEMBL9412299

CCOCCOc1nsc(SC(F)F)c1C#N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9412276 0.86 ALDH1A1 (0.37) ALDH1A1MAPTRECQL
SCHEMBL9412298 0.85 ALDH1A1 (0.36) ALDH1A1MAPTRECQL
SCHEMBL9412295 0.80 ALDH1A1 (0.33) ALDH1A1MAPTRECQL
SCHEMBL9412247 0.78 RECQL (0.36) ALDH1A1MAPTRECQL
SCHEMBL8945823 0.77 ALDH1A1 (0.38) ALDH1A1MAPT
SCHEMBL9412255 0.77 SQOR (0.34) ALDH1A1MAPT
SCHEMBL9412296 0.77 ALDH1A1 (0.33) ALDH1A1MAPTRECQL
SCHEMBL9412290 0.75 RECQL (0.34) ALDH1A1MAPTRECQL
SCHEMBL9412303 0.74 ALDH1A1 (0.36) ALDH1A1MAPTRECQL
SCHEMBL9412225 0.73 ALDH1A1 (0.44) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0578246-A1 Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient NIHON NOHYAKU CO., LTD. (JP) 1994-01-12 EP disclosed