Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 3/20 | 0.40 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307867 | 0.87 | DPP4 (0.49) | DPP4POLA1STAT3GDAKDR | |
| SCHEMBL9412617 | 0.86 | GDA (0.39) | DPP4STAT3GDAKDRAURKB | |
| SCHEMBL5197101 | 0.82 | GDA (0.54) | DPP4POLA1STAT3GDAXDH | |
| SCHEMBL9412610 | 0.80 | DPP4 (0.50) | DPP4POLA1STAT3GDAKDR | |
| SCHEMBL9412465 | 0.78 | JAK3 (0.32) | — | |
| SCHEMBL15063958 | 0.76 | SYK (0.52) | DPP4POLA1STAT3GDAXDH | |
| SCHEMBL27824249 | 0.73 | DPP4 (0.61) | DPP4POLA1GDAXDH | |
| SCHEMBL6551675 | 0.73 | DPP4 (0.56) | DPP4POLA1GDAXDHNEK2 | |
| Acetic Acid SCHEMBL7594624 | 0.72 | DPP4 (0.48) | DPP4POLA1STAT3GDAXDH | |
| SCHEMBL4777463 | 0.71 | GDA (0.42) | STAT3GDAKDRAURKBNEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590361-A1 | Process for the preparation of 2-amino-6-halopurines | BASF Aktiengesellschaft (DE) | 1994-04-06 | — | — | EP | disclosed |