Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 14/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251804 | 0.83 | TNF (0.56) | TNF | |
| SCHEMBL9412588 | 0.77 | TNF (0.57) | TNFHPGDALDH1A1 | |
| SCHEMBL1945518 | 0.77 | HPGD (0.55) | HPGDALDH1A1 | |
| SCHEMBL4252996 | 0.75 | KAT2B (0.45) | TNFALDH1A1 | |
| SCHEMBL7036408 | 0.75 | TNF (0.47) | TNFEP300 | |
| SCHEMBL9412660 | 0.73 | TNF (0.53) | TNFHPGDALDH1A1 | |
| SCHEMBL1546589 | 0.73 | HPGD (0.58) | HPGDALDH1A1 | |
| SCHEMBL11210331 | 0.73 | TNF (0.58) | TNFALDH1A1 | |
| SCHEMBL7040835 | 0.71 | TNF (0.50) | TNF | |
| SCHEMBL8104091 | 0.71 | FAAH (0.62) | TNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |