Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31301123 | 0.74 | GPR84 (0.67) | GPR84CTDSP1G6PDTYMP | |
| SCHEMBL5443895 | 0.67 | GPR84 (0.54) | GPR84RAB9AG6PDTYMPKDM4E | |
| SCHEMBL4447661 | 0.64 | GPR84 (0.47) | GPR84SMN1; SMN2G6PDTYMPGAA | |
| SCHEMBL16543124 | 0.62 | GPR84 (0.39) | GPR84CTDSP1RAB9ACDK1CDK4 | |
| SCHEMBL15018449 | 0.59 | GPR84 (0.39) | GPR84G6PDTYMPCDK1CDK4 | |
| SCHEMBL28181795 | 0.59 | JAK2 (0.53) | GPR84RAB9AG6PDCDK1CDK4 | |
| SCHEMBL27906010 | 0.53 | TSHR (0.36) | RAB9ATYMP | |
| SCHEMBL13420239 | 0.52 | RPS6KA3 (0.37) | SMN1; SMN2CTDSP1RAB9ANPC1TYMP | |
| SCHEMBL8408224 | 0.52 | RPS6KA3 (0.69) | SMN1; SMN2RAB9ANPC1GAAKDM4E | |
| SCHEMBL21941231 | 0.52 | RPS6KA3 (0.69) | SMN1; SMN2RAB9ANPC1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611660-A2 | Condensed 5-membered heterocycles, process for their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1994-08-24 | — | — | EP | disclosed |