Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 18/20 | 0.39 |
| ▸ | EDNRA | P25101 | 18/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295985 | 0.78 | EDNRB (0.40) | EDNRBEDNRAL3MBTL1LMNATDP1 | |
| SCHEMBL9412460 | 0.72 | RECQL (0.32) | — | |
| SCHEMBL9367315 | 0.69 | EDNRB (0.59) | EDNRBEDNRALMNATDP1 | |
| SCHEMBL9367683 | 0.68 | EDNRB (0.66) | EDNRBEDNRALMNATDP1 | |
| SCHEMBL7811183 | 0.67 | EDNRB (0.55) | EDNRBEDNRA | |
| SCHEMBL9296713 | 0.67 | EDNRB (0.47) | EDNRBEDNRAL3MBTL1LMNATDP1 | |
| SCHEMBL9372708 | 0.67 | EDNRB (0.64) | EDNRBEDNRALMNATDP1 | |
| SCHEMBL14298980 | 0.67 | L3MBTL1 (0.46) | EDNRBEDNRAL3MBTL1LMNATDP1 | |
| SCHEMBL6335452 | 0.66 | L3MBTL1 (0.48) | EDNRBEDNRAL3MBTL1LMNATDP1 | |
| SCHEMBL9412740 | 0.66 | EDNRB (0.43) | EDNRBEDNRAL3MBTL1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630890-A2 | Pyrimidine derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1994-12-28 | — | — | EP | disclosed |