Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981562 | 0.90 | DRD2 (0.43) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| SCHEMBL6981384 | 0.90 | DRD2 (0.43) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| SCHEMBL7811043 | 0.90 | DRD2 (0.43) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL6984757 | 0.89 | DRD2 (0.42) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL7811763 | 0.89 | DRD2 (0.42) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Bromide SCHEMBL7811682 | 0.89 | DRD2 (0.42) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Bromide SCHEMBL7811677 | 0.89 | DRD2 (0.42) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Hydrochloric Acid SCHEMBL6985847 | 0.89 | DRD2 (0.42) | SLC18A3DRD2ADRA1BSIGMAR1HTR7 | |
| Fumaric Acid SCHEMBL9412812 | 0.88 | SLC18A3 (0.37) | PRCPSLC18A3DRD2ADRA1DADRA1A | |
| Fumaric Acid SCHEMBL7802740 | 0.88 | SLC18A3 (0.37) | PRCPSLC18A3DRD2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601547-A1 | Crystalline salts of optically active aminocoumaran derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-15 | — | — | EP | disclosed |