Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412903 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1NPC1GAAL3MBTL1 | |
| SCHEMBL9413048 | 0.86 | NPC1 (0.52) | NPC1RAB9AHTR1ADRD2HTR2A | |
| SCHEMBL9413053 | 0.86 | NPC1 (0.52) | NPC1RAB9AHTR1ADRD2HTR2A | |
| SCHEMBL9413045 | 0.86 | CDK2 (0.52) | KDM4EALDH1A1NPC1L3MBTL1RAB9A | |
| SCHEMBL9413040 | 0.86 | CDK2 (0.52) | KDM4EALDH1A1NPC1L3MBTL1RAB9A | |
| SCHEMBL8714863 | 0.84 | NPC1 (0.56) | ALDH1A1NPC1L3MBTL1RAB9ASMYD3 | |
| SCHEMBL8714859 | 0.84 | NPC1 (0.56) | ALDH1A1NPC1L3MBTL1RAB9ASMYD3 | |
| SCHEMBL9412956 | 0.83 | SMN1; SMN2 (0.59) | KDM4ENPC1RAB9AHTR1ADRD2 | |
| SCHEMBL9412960 | 0.83 | SMN1; SMN2 (0.59) | KDM4ENPC1RAB9AHTR1ADRD2 | |
| SCHEMBL8714762 | 0.83 | NPC1 (0.57) | KDM4ENPC1GAARAB9ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623621-A1 | Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |