Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412956 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2FLT3HTR1ADRD2HTR2A | |
| SCHEMBL9413040 | 0.91 | CDK2 (0.52) | SMN1; SMN2FLT3HTR1AHTR2AHTR2C | |
| SCHEMBL9413045 | 0.91 | CDK2 (0.52) | SMN1; SMN2FLT3HTR1AHTR2AHTR2C | |
| SCHEMBL8714859 | 0.87 | NPC1 (0.56) | SMN1; SMN2FLT3NPC1RAB9ASMYD3 | |
| SCHEMBL8714863 | 0.87 | NPC1 (0.56) | SMN1; SMN2FLT3NPC1RAB9ASMYD3 | |
| SCHEMBL9413011 | 0.87 | MEN1 (0.52) | SMN1; SMN2HTR1ADRD2HTR2ANPC1 | |
| SCHEMBL9413006 | 0.87 | MEN1 (0.52) | SMN1; SMN2HTR1ADRD2HTR2ANPC1 | |
| SCHEMBL9412903 | 0.83 | KDM4E (0.59) | SMN1; SMN2HTR1ADRD2HTR2ANPC1 | |
| SCHEMBL9412888 | 0.83 | RAB9A (0.49) | SMN1; SMN2FLT3HRH1NPC1RAB9A | |
| SCHEMBL9412887 | 0.83 | RAB9A (0.49) | SMN1; SMN2FLT3HRH1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623621-A1 | Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |