Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413040 | 1.00 | CDK2 (0.52) | CDK2FLT3NPC1RAB9AHTR1A | |
| SCHEMBL9412960 | 0.91 | SMN1; SMN2 (0.59) | CDK2FLT3NPC1RAB9AHTR1A | |
| SCHEMBL9412956 | 0.91 | SMN1; SMN2 (0.59) | CDK2FLT3NPC1RAB9AHTR1A | |
| SCHEMBL8714863 | 0.90 | NPC1 (0.56) | FLT3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8714859 | 0.90 | NPC1 (0.56) | FLT3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9413079 | 0.89 | RAB9A (0.56) | FLT3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9413073 | 0.89 | RAB9A (0.56) | FLT3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9226450 | 0.88 | RAB9A (0.55) | FLT3NPC1RAB9AHTR1AHTR2A | |
| SCHEMBL9226452 | 0.88 | RAB9A (0.55) | FLT3NPC1RAB9AHTR1AHTR2A | |
| SCHEMBL9412888 | 0.86 | RAB9A (0.49) | FLT3NPC1RAB9AHRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623621-A1 | Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |