Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034860 | 0.87 | KMT2A (0.51) | KMT2ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL9412884 | 0.83 | DRD4 (0.44) | KMT2ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL9412886 | 0.83 | DRD4 (0.44) | KMT2ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL9412858 | 0.81 | DRD2 (0.41) | POLBDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL853058 | 0.80 | CHRM2 (0.49) | KMT2ASMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL15421246 | 0.80 | CHRM2 (0.49) | KMT2ASMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL10106310 | 0.80 | CHRM2 (0.49) | KMT2ASMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL4039348 | 0.79 | DRD2 (0.48) | KMT2ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL7497519 | 0.78 | DRD4 (0.43) | KMT2ASMN1; SMN2POLBDRD2DRD4 | |
| SCHEMBL9413133 | 0.77 | KDM4E (0.42) | SMN1; SMN2TRAP1MAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623621-A1 | Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |