SCHEMBL853058

SCHEMBL853058

O=C1CC2COCC(C1)N2Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.49
CHRM4 P08173 1/20 0.49
CHRM5 P08912 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.40
CHRM3 P20309 1/20 0.40
F2 P00734 1/20 0.40
PLG P00747 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
CMA1 P23946 1/20 0.40
CTRC Q99895 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15421246 1.00 CHRM2 (0.49) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL10106310 1.00 CHRM2 (0.49) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL21548123 0.90 CHRM2 (0.43) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL6153627 0.88 CHRM2 (0.56) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL636999 0.86 CHRM2 (0.58) CHRM2CHRM4CHRM5L3MBTL1KMT2A
SCHEMBL29691892 0.84 CHRM2 (0.53) CHRM2CHRM4CHRM5L3MBTL1ALDH1A1
SCHEMBL707808 0.84 CHRM2 (0.53) CHRM2CHRM4CHRM5L3MBTL1ALDH1A1
SCHEMBL719296 0.84 CHRM2 (0.53) CHRM2CHRM4CHRM5L3MBTL1ALDH1A1
SCHEMBL19364501 0.84 CHRM2 (0.53) CHRM2CHRM4CHRM5L3MBTL1ALDH1A1
SCHEMBL16766368 0.84 CHRM2 (0.53) CHRM2CHRM4CHRM5L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 EP disclosed
US-20260042776-A1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2026-02-12 US disclosed
US-12486285-B2 BCL6 inhibitors CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2025-12-02 US disclosed
CN-113382767-B Urea compounds having substituents 第一三共株式会社 2024-12-24 CN disclosed
US-11981686-B2 Urea compound having substituent DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-14 US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 US disclosed
EP-4201939-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2023-06-28 EP disclosed
US-20230058950-A1 UREA COMPOUND HAVING SUBSTITUENT DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-02-23 US disclosed
US-20230058950-A1 UREA COMPOUND HAVING SUBSTITUENT DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-02-23 US disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 EP disclosed
WO-2005103054-A2 BRIDGED PIPERAZINE AND PIPERIDINE DERIVATIVES AS CCRI ANTAGONISTS NOVARTIS AG (CH) 2005-11-03 WO disclosed
US-6586430-B1 Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders PFIZER INC. 2003-07-01 US disclosed
US-5641786-A Quinuclidine derivatives LOWE III JOHN ADAMS (US) 1997-06-24 US disclosed
US-5422354-A Quinuclidine derivatives PFIZER INC (US) 1995-06-06 US disclosed
EP-0540526-B1 QUINUCLIDINE DERIVATIVES PFIZER (US) 1994-12-28 EP disclosed
EP-0623621-A1 Oxazabicyclo derivatives and their use as 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO., LTD. (JP) 1994-11-09 EP disclosed
EP-0540526-A1 QUINUCLIDINE DERIVATIVES. PFIZER (US) 1993-05-12 EP disclosed
WO-1992001688-A1 QUINUCLIDINE DERIVATIVES PFIZER INC. (US) 1992-02-06 WO disclosed
US-4352802-A DESALINATION OF SEA WATER BEECHAM GROUP LIMITED (GB) 1982-10-05 US disclosed
EP-0041817-A1 Benzamide derivatives, process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-12-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981686-B2 Urea compound having substituent SIRT6, SIRT1, SIRT2 CHRM2 2071/4885CHRM4 3251/4885CHRM5 2947/4885
US-20230287003-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-20230058950-A1 UREA COMPOUND HAVING SUBSTITUENT SIRT6, SIRT1, SIRT2 CHRM2 2071/4885CHRM4 3251/4885CHRM5 2947/4885
US-12486285-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 CHRM2 4751/4885CHRM4 4697/4885CHRM5 4734/4885
US-20260042776-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL9 CHRM2 4733/4885CHRM4 4720/4885CHRM5 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.