Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.59 |
| ▸ | PRKCG | P05129 | 2/20 | 0.59 |
| ▸ | PRKCB | P05771 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | PRKCA | P17252 | 2/20 | 0.59 |
| ▸ | PRKCH | P24723 | 2/20 | 0.59 |
| ▸ | PRKCI | P41743 | 2/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.59 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413540 | 0.81 | EGFR (0.59) | EGFRMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9413538 | 0.81 | BRAF (0.76) | EGFRMEN1MAPTKMT2APRKD3 | |
| Cgp-53353 SCHEMBL29766901 | 0.74 | EGFR (1.00) | EGFRMEN1MAPTKMT2APRKD3 | |
| Cgp-53353 SCHEMBL230492 | 0.74 | EGFR (1.00) | EGFRMEN1MAPTKMT2APRKD3 | |
| SCHEMBL3110885 | 0.71 | DAO (0.69) | MAPTDAOKDM4EALDH1A1POLB | |
| SCHEMBL29377177 | 0.71 | MAPT (0.55) | EGFRMEN1MAPTKMT2APRKD3 | |
| SCHEMBL8833907 | 0.70 | EGFR (0.69) | EGFRMEN1MAPTKMT2APRKD3 | |
| SCHEMBL3410898 | 0.69 | MEN1 (0.41) | EGFRMEN1MAPTKMT2APRKD3 | |
| SCHEMBL8834604 | 0.68 | EGFR (0.84) | EGFRMEN1MAPTKMT2APRKD3 | |
| SCHEMBL8834266 | 0.68 | DHODH (0.53) | EGFRMEN1MAPTKMT2APRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600831-A1 | Phtalazinon derivatives | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600831-A1 | Phtalazinon derivatives | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |