Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25474391 | 0.93 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25474388 | 0.93 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9413695 | 0.83 | NPC1 (0.37) | SLC6A3NPC1RAB9AHPGDALOX12 | |
| SCHEMBL7453051 | 0.83 | PKM (0.40) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL9152577 | 0.82 | FFAR1 (0.51) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9153434 | 0.81 | NPC1 (0.42) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL25224758 | 0.80 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9153116 | 0.80 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3NPC1RAB9A | |
| SCHEMBL7428096 | 0.79 | MEN1 (0.55) | MEN1KMT2APKMCTDSP1 | |
| SCHEMBL966816 | 0.78 | MEN1 (0.58) | MEN1KMT2APKMCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082041-A | The phenylpropionic acid of imidazolyl-replacement and cinnamic acid derivative | BAYER AG (DE) | 1994-02-16 | — | — | CN | disclosed |
| EP-0578002-A1 | Imidazolyl substituted phenylpropionic and cinnamic acid derivatives | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |