Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152577 | 0.87 | FFAR1 (0.51) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL9150014 | 0.82 | FFAR1 (0.44) | NPC1RAB9AMEN1KMT2AEPHX1 | |
| SCHEMBL27396211 | 0.81 | MEN1 (0.41) | MEN1KMT2AEPHX1FFAR1CYP3A4 | |
| SCHEMBL9413697 | 0.81 | SLC6A2 (0.41) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL9413682 | 0.81 | GPR119 (0.39) | NPC1RAB9AMEN1KMT2AFFAR1 | |
| SCHEMBL18501542 | 0.78 | FFAR1 (0.43) | NPC1RAB9AKMT2AFFAR1 | |
| SCHEMBL18501544 | 0.78 | FFAR1 (0.43) | NPC1RAB9AKMT2AFFAR1 | |
| SCHEMBL7453051 | 0.77 | PKM (0.40) | NPC1RAB9AMEN1KMT2AC3AR1 | |
| SCHEMBL27396973 | 0.74 | MEN1 (0.42) | NPC1RAB9AMEN1KMT2AEPHX1 | |
| SCHEMBL9413695 | 0.74 | NPC1 (0.37) | NPC1RAB9AMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414008-A | Hypotensive and antiatherosclerotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0578002-A1 | Imidazolyl substituted phenylpropionic and cinnamic acid derivatives | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |