Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17377711 | 0.86 | LMNA (0.57) | LMNAKMT2ACYP2D6CYP2C9POLB | |
| SCHEMBL2225143 | 0.79 | — | — | |
| SCHEMBL15233814 | 0.76 | LMNA (0.44) | LMNAITGB1ITGA4KMT2ACYP2D6 | |
| SCHEMBL12764294 | 0.75 | ITGB1 (0.38) | LMNAITGB1ITGA4KMT2ACYP2D6 | |
| SCHEMBL11167675 | 0.73 | ITGB1 (0.37) | LMNAITGB1ITGA4KMT2ACYP2D6 | |
| SCHEMBL13430349 | 0.73 | ITGB1 (0.37) | LMNAITGB1ITGA4KMT2ACYP2D6 | |
| SCHEMBL6538147 | 0.72 | — | — | |
| SCHEMBL4728242 | 0.72 | — | — | |
| SCHEMBL14140164 | 0.72 | — | — | |
| SCHEMBL9744059 | 0.72 | LMNA (0.34) | LMNAITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597401-A2 | Production of penem | Takeda Chemical Industries, Ltd. (JP) | 1994-05-18 | — | — | EP | disclosed |
| US-4751297-A | ANTIBIOTIC INTERMEDIATES | PFIZER INC. (US) | 1988-06-14 | — | — | US | disclosed |