Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15270870 | 0.84 | PAOX (0.32) | KDM4ETGFBR1 | |
| SCHEMBL16271563 | 0.84 | KMT2A (0.37) | TGFBR1MEN1KMT2A | |
| SCHEMBL18331598 | 0.83 | KDM4E (0.42) | KDM4E | |
| SCHEMBL11344769 | 0.83 | TGFBR1 (0.35) | TGFBR1MAPT | |
| SCHEMBL109244 | 0.83 | KDM5A (0.34) | KDM4ETGFBR1 | |
| SCHEMBL14356797 | 0.83 | TGFBR1 (0.35) | KDM4ETGFBR1MAPT | |
| SCHEMBL18331463 | 0.83 | KDM4E (0.42) | KDM4E | |
| SCHEMBL18331597 | 0.83 | KDM4E (0.42) | KDM4E | |
| SCHEMBL522742 | 0.82 | KDM4C (0.41) | KDM4EMEN1KMT2A | |
| SCHEMBL18331532 | 0.81 | KDM4E (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362458-A1 | SWITCHABLE ANTIMICROBIAL AND ANTIFOULING CARBOXYBETAINE-BASED HYDROGELS AND ELASTOMERS WITH ENHANCED MECHANICAL PROPERTIES | THE UNIVERSITY OF AKRON (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362458-A1 | SWITCHABLE ANTIMICROBIAL AND ANTIFOULING CARBOXYBETAINE-BASED HYDROGELS AND ELASTOMERS WITH ENHANCED MECHANICAL PROPERTIES | THE UNIVERSITY OF AKRON (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170362458-A1 | SWITCHABLE ANTIMICROBIAL AND ANTIFOULING CARBOXYBETAINE-BASED HYDROGELS AND ELASTOMERS WITH ENHANCED MECHANICAL PROPERTIES | THE UNIVERSITY OF AKRON (US) | 2017-12-21 | — | — | US | disclosed |
| WO-2014194268-A1 | SWITCHABLE ANTIMICROBIAL AND ANTIFOULING CARBOXYBETAINE-BASED HYDROGELS | THE UNIVERSITY OF AKRON (US) | 2014-12-04 | — | — | WO | disclosed |
| EP-0604844-A1 | Process for the preparation of trialkylammoniumalkyl (meth)acrylate compounds | RÖHM GMBH (DE) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362458-A1 | SWITCHABLE ANTIMICROBIAL AND ANTIFOULING CARBOXYBETAINE-BASED HYDROGELS AND ELASTOMERS WITH ENHANCED MECHANICAL PROPERTIES | PTMS, PCNA, DDB1 | KDM4E 489/4885TGFBR1 207/4885THRA 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.