Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8719903 | 0.99 | HDAC8 (0.45) | HDAC8KMT2AMEN1POLBUSP2 | |
| SCHEMBL8303647 | 0.79 | HDAC8 (0.45) | HDAC8KMT2AMEN1USP2KDM4E | |
| SCHEMBL8304894 | 0.78 | HDAC8 (0.40) | HDAC8PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9414691 | 0.78 | HDAC8 (0.38) | HDAC8KMT2AMEN1POLBPSEN1 | |
| SCHEMBL8307154 | 0.78 | HDAC8 (0.52) | HDAC8KMT2AMEN1CA1CA2 | |
| Hydrochloric Acid SCHEMBL8718128 | 0.78 | HDAC8 (0.37) | HDAC8KMT2AMEN1POLBPSEN1 | |
| SCHEMBL8715200 | 0.78 | PDE4A (0.48) | HDAC8KMT2AMEN1POLBPSEN1 | |
| SCHEMBL8305943 | 0.77 | HDAC8 (0.37) | HDAC8KMT2AMEN1POLBPSEN1 | |
| SCHEMBL8308496 | 0.76 | ALDH1A1 (0.52) | HDAC8KMT2AMEN1POLBUSP2 | |
| SCHEMBL8304185 | 0.74 | HDAC8 (0.37) | HDAC8PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |