SCHEMBL9415876

SCHEMBL9415876

O/N=C1\CCc2cccc(O)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
HPN P05981 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
PTGS1 P23219 1/20 0.42
PDE4A P27815 1/20 0.42
KDR P35968 1/20 0.42
KMT2A Q03164 1/20 0.42
SIRT5 Q9NXA8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9415879 1.00 HSD17B10 (0.50) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL12023190 0.80 ALDH1A1 (0.54) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL26404090 0.78 LMNA (0.49) HSD17B10LMNAL3MBTL1MAPTALDH1A1
SCHEMBL25298618 0.78 LMNA (0.49) HSD17B10LMNAL3MBTL1MAPTALDH1A1
SCHEMBL2045887 0.78 KDM1A (0.38) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL2045889 0.78 KDM1A (0.38) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL6095661 0.74 HSD17B10 (0.45) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL6095668 0.74 HSD17B10 (0.45) HSD17B10LMNAL3MBTL1MAPTTDP1
SCHEMBL659339 0.74 LMNA (0.45) HSD17B10LMNAMAPTALDH1A1MEN1
SCHEMBL659340 0.74 LMNA (0.45) HSD17B10LMNAMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6239812-A None JP disclosed
JP-H06239812-A PRODUCTION OF 1-AMINO-2,3-DIHYDRO-7-HYDROXY-1H-INDENE DERIVATIVE OTSUKA PHARMACEUT CO LTD 1994-08-30 JP disclosed