Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9123221 | 0.99 | ADRA1A (0.53) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| SCHEMBL9416152 | 0.91 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9124065 | 0.90 | ADRA1A (0.64) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| SCHEMBL14301033 | 0.88 | ADRA1A (0.70) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9125870 | 0.84 | GAA (0.53) | ADRA1AADRB2HTR1ADRD2DRD3 | |
| SCHEMBL9416163 | 0.82 | ADRB2 (0.65) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| SCHEMBL12453523 | 0.82 | ADRA1A (0.80) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9123410 | 0.81 | ADRB2 (0.64) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| SCHEMBL9125314 | 0.80 | ADRB2 (0.73) | ADRA1AADRA1DADRA1BADRB2HTR1A | |
| SCHEMBL11473050 | 0.79 | ADRB2 (0.85) | ADRA1AADRA1DADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585067-A1 | Use of certain sulfamoyl-substituted phenethylamine derivatives to reverse drug-induced mydriasis | ALCON LABORATORIES, INC. (US) | 1994-03-02 | — | — | EP | claimed |