Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114605 | 0.90 | PIK3CG (0.42) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL27879215 | 0.86 | PTGDR2 (0.41) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL9416403 | 0.85 | KDM4E (0.41) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL10756839 | 0.85 | KDM4E (0.40) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL3815099 | 0.83 | KDM4E (0.59) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL30906935 | 0.83 | KDM4E (0.59) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL10862667 | 0.82 | KDM4E (0.60) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7851039 | 0.81 | PIK3CG (0.36) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL10863489 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E | |
| SCHEMBL6240583 | 0.81 | ALDH1A1 (0.47) | PIK3CDPIK3R1PIK3CAPIK3CGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0117473-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0117474-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1986-10-29 | — | — | EP | disclosed |
| EP-0121727-B1 | BACTERICIDAL AGENT BASED ON QUINOLONECARBOXYLIC ACIDS | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |
| EP-0113091-B1 | MICROBIOCIDAL AGENTS BASED ON QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0118854-B1 | BACTERICIDAL AGENT CONTAINING QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| EP-0121727-A1 | Bactericidal agent based on quinolonecarboxylic acids | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0118854-A1 | Bactericidal agent containing quinolone-carboxylic acids | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0117473-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0113091-A1 | Microbiocidal agents based on quinolone-carboxylic acids | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |