Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416407 | 0.85 | CNR2 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10862874 | 0.84 | POLB (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL5544803 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL30906937 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3234629 | 0.82 | TP53 (0.50) | P2RX3POLBCNR2 | |
| SCHEMBL3234265 | 0.82 | EGLN2 (0.46) | MAPK8P2RX3CNR2 | |
| SCHEMBL10863325 | 0.81 | NR4A2 (0.52) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL10706702 | 0.81 | HPGD (0.40) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3239683 | 0.80 | P2RX3 (0.43) | MAPK8P2RX3POLBCNR2 | |
| SCHEMBL3241020 | 0.80 | SLC22A12 (0.45) | MAPK8P2RX3MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |