Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613565 | 0.94 | ADRB2 (0.63) | ADRB2LMNAOXTRAVPR1AHTT | |
| SCHEMBL8616198 | 0.92 | CCR3 (0.53) | ADRB2LMNAHTTCCR3OPRM1 | |
| SCHEMBL24322660 | 0.79 | MEN1 (0.58) | CCR3OPRM1ALDH1A1NPSR1MEN1 | |
| SCHEMBL8612921 | 0.79 | MEN1 (0.58) | CCR3OPRM1ALDH1A1NPSR1MEN1 | |
| SCHEMBL9147179 | 0.78 | KMT2A (0.48) | HTTOPRM1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31650952 | 0.75 | HTT (0.69) | LMNAHTTALDH1A1TSHRMEN1 | |
| SCHEMBL9143775 | 0.74 | KMT2A (0.49) | ADRB2LMNAHTTOPRM1ALDH1A1 | |
| SCHEMBL11257835 | 0.74 | ADRB2 (1.00) | ADRB2LMNAOXTRAVPR1AHTT | |
| Tamolarizine SCHEMBL331314 | 0.73 | KMT2A (0.67) | ADRB2LMNAHTTADRB1ADRB3 | |
| Tamolarizine SCHEMBL2194434 | 0.72 | MEN1 (0.65) | ADRB2ADRB1ADRB3OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |