Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 2/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | TSPO | P30536 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416603 | 0.94 | SLC2A1 (0.57) | HSD17B2MTNR1AMTNR1BTSPOSLC2A1 | |
| SCHEMBL16316850 | 0.88 | ROCK2 (0.55) | HSD17B2MTNR1AMTNR1BTSPOPTGES | |
| SCHEMBL29234302 | 0.87 | TSHR (0.57) | HSD17B2TSPOPTGESSLC2A1SLC2A4 | |
| SCHEMBL29469525 | 0.87 | TSHR (0.57) | HSD17B2TSPOPTGESSLC2A1SLC2A4 | |
| SCHEMBL24344639 | 0.85 | HSD17B2 (0.56) | HSD17B2MTNR1AMTNR1BTSPOPTGES | |
| SCHEMBL30246316 | 0.85 | HSD17B2 (0.56) | HSD17B2MTNR1AMTNR1BTSPOPTGES | |
| SCHEMBL7179678 | 0.85 | HSD17B2 (0.56) | HSD17B2MTNR1AMTNR1BTSPOPTGES | |
| SCHEMBL6417242 | 0.85 | HSD17B2 (0.63) | HSD17B2MTNR1AMTNR1BCYP1A2BCHE | |
| SCHEMBL24344606 | 0.83 | SLC2A1 (0.56) | HSD17B2TSPOPTGESSLC2A1SLC2A4 | |
| SCHEMBL30945862 | 0.83 | TSPO (0.54) | HSD17B2MTNR1AMTNR1BTSPOPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |