Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 17/20 | 0.83 |
| ▸ | HSD17B1 | P14061 | 16/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495942 | 0.91 | HSD17B2 (1.00) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL9416649 | 0.89 | HSD17B1 (0.71) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL12688094 | 0.87 | HSD17B2 (1.00) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL12495845 | 0.84 | HSD17B2 (1.00) | HSD17B2HSD17B1 | |
| SCHEMBL19049387 | 0.81 | HSD17B2 (0.61) | HSD17B2HSD17B1 | |
| SCHEMBL17119847 | 0.81 | HSD17B1 (0.57) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL18773897 | 0.81 | KMT2A (0.69) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL12688057 | 0.80 | HSD17B2 (1.00) | HSD17B2HSD17B1 | |
| SCHEMBL11899205 | 0.79 | HSD17B1 (0.56) | HSD17B2HSD17B1KMT2AMEN1 | |
| SCHEMBL28897045 | 0.79 | HSD17B1 (0.55) | HSD17B2HSD17B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |