Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29207901 | 0.93 | SMN1; SMN2 (0.66) | LMNASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL1599701 | 0.91 | KDM4E (0.69) | LMNASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL29484286 | 0.91 | KDM4E (0.69) | LMNASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL3051565 | 0.89 | LMNA (0.74) | LMNASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL11063684 | 0.89 | TTR (0.66) | LMNASMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL9416614 | 0.88 | LMNA (0.73) | LMNASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL1966824 | 0.87 | KDM4E (0.74) | LMNASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL5031143 | 0.87 | BCHE (0.74) | LMNASMN1; SMN2HTTKMT2AKDM4E | |
| SCHEMBL7279400 | 0.85 | ALDH1A1 (0.72) | LMNASMN1; SMN2HTTKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11451398 | 0.85 | KDM4E (0.72) | LMNASMN1; SMN2HTTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
| US-5621103-A | 3-(SUBSTITUTED METHYLAMINOCARBONYL)-1,2,3,4-TETRAHYDRO-(1)BENZOTHIENO(2,3-C) PYRIDINES; ANXIOLYTIC AGENTS; LEARNING ENHANCEMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0253327-B1 | DIPHENYLPROPYLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-06 | — | — | EP | disclosed |
| EP-0253327-A2 | Diphenylpropylamine derivatives, their preparation and their pharmaceutical use | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-01-20 | — | — | EP | disclosed |
| US-4435565-A | ENZYME INHIBITORS | BEECHAM GROUP LIMITED (GB) | 1984-03-06 | — | — | US | disclosed |
| US-4359473-A | α-Amino deoxy clavulanic acid antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1982-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | LMNA 3312/4885SMN1; SMN2 4582/4885MAPT 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.