Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.46 |
| ▸ | GLI2 | P10070 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416531 | 0.89 | PPARG (0.59) | HDAC1HDAC6HSD17B1HSD17B2PPARG | |
| SCHEMBL9416649 | 0.80 | HSD17B1 (0.71) | HDAC1HDAC6HSD17B1HSD17B2KMT2A | |
| SCHEMBL1926269 | 0.79 | HDAC1 (0.73) | HDAC1HDAC6HDAC3HDAC2KMT2A | |
| SCHEMBL9416548 | 0.77 | MEN1 (0.60) | HDAC1HDAC6KMT2AL3MBTL1LPAR1 | |
| SCHEMBL4352375 | 0.77 | HDAC1 (0.50) | HDAC1HDAC6LTB4R2PKMTDP1 | |
| SCHEMBL1867393 | 0.77 | HPGD (0.69) | HPGDTDP1 | |
| SCHEMBL13911243 | 0.77 | LIMK1 (0.65) | HDAC1HDAC6PPARGKMT2AL3MBTL1 | |
| SCHEMBL9361376 | 0.77 | TP53 (0.60) | HDAC1HDAC6BACE1KMT2AL3MBTL1 | |
| SCHEMBL4489409 | 0.77 | MLYCD (0.64) | HDAC1HDAC6BACE1HPGDTDP1 | |
| SCHEMBL28897045 | 0.76 | HSD17B1 (0.55) | BACE1HSD17B1HSD17B2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |